Still blaming your hormones for normal menstrual and menopausal symptoms like mild cramps, premenstrual breast tenderness, PMS, mood swings, hot flashes, vaginal dryness and more?* While hormonal changes do play their part, the latest science says there is more to the story. 

New research shows that micronutrients like amino acids, lipids and vitamins fluctuate depending on the phases of your menstrual cycle and as you approach menopause. And these nutrient fluctuations can play a big role in how you feel physically, mentally and emotionally. 

What does this cutting-edge science mean when it comes to reducing normal menstrual and menopausal symptoms? It means that instead of turning to products that contain hormones or hormone-like ingredients, such as soy isoflavones, to help stabilize normal and mild menstrual and menopausal ups and downs, focusing on nutrition may be a more effective — and intuitive — approach. 

Unfortunately, most women’s health supplements fall short of this approach in several ways. From only offering one formula to take all month long instead of syncing nutrients to the phases of your cycle, to providing cookie-cutter ingredients that only address a handful of normal symptoms or formulating with ingredients known to pose potential risks with long-term use, it’s no wonder so many women accept normal and mild menstrual and menopausal ups and downs as inevitable. 

And as if finding the right supplements weren’t hard enough, there’s a key component to wellness that most people overlook: Your body can’t optimize all nutrients without a healthy gut microbiome. 

So, question #1: How do you support a healthy gut microbiome? And question #2: Once your gut is able to optimize nutrient absorption, which nutrients do you need to support hormonal health and when? 


Your microbiome comprised of an estimated 38 trillion microorganisms, the majority of which live in your gut. And when your microbiome isn’t populated with enough good bacteria, it affects the integrity of your gut lining, which is directly responsible for how efficiently your body absorbs nutrients from the foods you eat and the supplements you take. 

Your gut lining also plays a role in how efficiently your body flushes out waste. For the 90% of women who report occasional digestive discomfort, balanced gut microbiota can help reduce occasional bloating, constipation and loose stool, especially around your period.

And your gut lining plays a key role in metabolizing excess estrogen, helping the body as it keeps estrogen levels within optimal range. What’s more, all this detoxification is critical in supporting a strong immune system, 70% of which is housed in the gut. 

And let’s not forget occasional anxiousness, increased stress, poor sleep quality and brain fog. These normal menstrual and menopausal symptoms are also linked to gut health. Your microbiome communicates along an information superhighway called the Gut-Brain Axis, relaying messages between your digestive system and your neurological system. It’s essential in the body’s normal production of dopamine and serotonin, known as your “happy hormones”, critical to brain and cognitive health. 

To recap, a healthy and diverse microbiome helps: 

  • Support the gut lining for optimal nutrient absorption 
  • Flush out waste, including supporting the body as it metabolizes excess estrogen 
  • Reduce occasional bloating and constipation 
  • Support immune health 
  • Support brain and cognitive function 

It’s no wonder your microbiome is called your master switch to wellness! But to effectively help turn it on, you need three key components… and most gut health formulas only deliver one. Keep reading to discover the easiest and most comprehensive way to support your microbiome. 


Axis Trebiotic on a plain background.

While most probiotics only target digestive health, Modere Axis™ TreBiotic features a first of its kind 3-in-1 Microbiome Matrix™ Technology, providing perfectly paired prebiotics, probiotics AND postbiotics in every scoop. 

The first component of the Microbiome Matrix is NeuroFlora™ Probiotic Complex, 3 strains of gram-positive beneficial bacteria highly studied for their ability to deliver benefits beyond gut health for overall microbiome support. This complex features Lactobacillus plantarum DR7, which when paired with GOS Prebiotic, the second component of the matrix, is shown in-vitro to populate faster and with greater density so you can feel benefits sooner.* 

What’s more, this cutting-edge formula includes revolutionary EpiCor® GI + postbiotics, the third component of Microbiome Matrix, backed by 15 scientific studies. This one-of-a-kind whole food fermentate supports healthy levels of butyrate and helps reinforce a protective gut lining to optimize nutrient synthesis.* 

How to use: 

Axis TreBiotic features unique beadlets and delivers acid-resistant bacteria, prebiotics and postbiotics. Sprinkle one scoop onto food, stir into a smoothie or take directly by mouth daily. 

Pro tip: 

We love Axis TreBiotic sprinkled onto peanut butter toast or mixed with gut-friendly Greek yogurt, berries and granola. 

So, now that you know where to find comprehensive support for your gut to optimize nutrient absorption, let’s discuss where to find the intuitive nutrition women need for optimal hormonal health during your menstrual cycle and the phases of menopause.* 


Modere Ova™ and Modere Ova™-m change the way you think about your period, perimenopause, menopause and post-menopause. Hormone-free and soy isoflavone-free, the Ova line delivers intuitive nutrition formulated for women, by women, to support hormonal health with clean label bioceuticals including essential vitamins and minerals, potent botanicals, antioxidants and more.* 

Modere Ova™ 

Modere Ova on a plain background.

For menstruating women, Ova is finely tuned to your unique cycle. Instead of just one formula to take all month long (like most menstrual health supplements) it offers 3 proprietary, science-backed formulas that target your period, pre-ovulation and post-ovulation: RELEASE, RENEW and BALANCE. 

RELEASE is formulated with Menstrual D-Tox Complex™ to help support detoxification and healthy blood flow during your period, reducing mild and occasional period discomfort during the first 4 days of your cycle.* 

RENEW features Bio-Optimal Pre-Ov Blend™ with ingredients that support hormones leading up to ovulation and promotes healthy libido and improved energy as the body’s estrogen levels normally rise days 5-16.* 

BALANCE targets mild symptoms of PMS with Co-Active PMS Matrix™, featuring ingredients for both physical and mental wellbeing, and is taken starting on day 17 until your next period begins.* 

How to use: 

Ova is packaged in a smart blister pack easily customizable with your unique cycle length. Take one capsule daily starting on the first day of your period with RELEASE in the first row of your blister pack. Then cycle through RENEW and BALANCE. When your next period begins, discontinue BALANCE and start a new box of Ova. In case your period starts before your next box of Ova arrives, extra RELEASE pills are provided in the bottom row of each blister pack. 

Pro tip: 

Always take Ova with food and a full glass of water! 

Modere Ova™-m 

Modere Ova-m on a plain background

To support the unique needs of menopausal women, Ova-m is a comprehensive formula that targets perimenopause, menopause and post-menopause. Featuring proprietary Estro-OS™ Complex, Ova-m delivers ingredients shown to support normal menopausal symptoms and vaginal dryness better than soy isoflavones.*† 

From helping to reduce mild hot flashes and night sweats to supporting cognitive health and cardiovascular health, Ova-m helps you feel like yourself again every day. Plus, it optimizes mood and energy levels.* 

How to use: 

Take 2 Ova-m pills once daily throughout perimenopause, menopause and post-menopause, continuing as long as unwanted normal and mild symptoms like hot flashes, vaginal dryness or brain fog persist. Unlike soy isoflavones which have been linked to health risks with long-term use, Ova-m is formulated to provide comprehensive support through all three phases of menopause, which can last 10 years or more.* 

Pro tip: 

For best results, take Ova-m with food and water at the same time daily. If mild night sweats are a concern, some women find taking Ova-m before bed works best.* 


Modere Ova and Ova-m alongside two bottles of Axis Trebiotic.

Until now, relying on a hormone-based approach to manage normal and mild menstrual and menopausal ups and downs has been the norm for most women. But the latest science shows your body’s hormonal response is intrinsically linked to nutrition. Only Modere Ova and Ova-m empower your body to find balance, delivering intuitive nutrition for optimal hormonal health and providing the right support at the right time, without hormones or soy isoflavones.* 

Ova Balanced Body Systems deliver the benefits of Ova paired with Axis TreBiotic to simultaneously promote a healthy gut lining for optimal nutrient absorption. So you can get the most out of your hormonal health supplements, plus reap additional benefits for gut, immune and cognitive health.* 

For too long, too many women have tolerated mild or occasional period cramps, breast tenderness, mood swings, low libido, vaginal dryness and hot flashes as a fact of life. Now it’s time to reinvent your hormone story with Modere. Choose Modere, clean label health to help women live well.* 

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.